Factors affecting gene expression

i Know that transcription factors are proteins that bind to DNA.

ii Understand the role of transcription factors in regulating gene expression.

iii Understand how post–transcription modification of mRNA in eukaryotic cells (RNA splicing) can result in different products from a single gene.

iv Understand that gene expression can be changed by epigenetic modification, including non-coding RNA, histone modification and DNA methylation.

v Know that epigenetic modification is important in ensuring cell differentiation.