Biology (Combined Science) · GCSE · OCR · OCR GCSE Combined Science A (Gateway Science) — Biology — Higher (J250) · Specification point · B1.2 · Cell level systems
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B1.2 What happens in cells (and what do cells need)?
Summary Life processes depend on biological molecules whose structure is related to their function. Inside every cell is genetic material and this is used as a code to make proteins. Enzymes are important proteins in biology. Underlying knowledge and understanding Learners should have a simple understanding of the double helix model of DNA. Learners should be familiar with the idea of enzymes as biological catalysts.
Common misconceptions Learners commonly hold the misconception that DNA is made of protein or sugar. Learners also think that all enzymes have an optimum temperature of 37°C (human body temperature). The range of optimum temperatures of enzymes should be introduced through the teaching of this topic and further addressed when considering homeostatic mechanisms for controlling temperature.
| Reference | Mathematical learning outcomes | Maths skills |
|---|---|---|
BM1.2i | carry out rate calculations for chemical reactions | M1a and M1c |
| Learning outcomes | To include |
|---|
| Maths |
|---|
| Working scientifically |
|---|
| Practical suggestions |
|---|
DNA and protein synthesis | ||||
B1.2a describe DNA as a polymer | WS1.4a | Demonstrate of the structure of DNA by constructing 3D models. | ||
B1.2b describe DNA as being made up of two strands forming a double helix | ||||
B1.2c describe experiments that can be used to investigate enzymatic reactions | M1a, M1c, M2g | WS1.1h, WS1.2b, WS1.2c, WS1.2e, WS1.3a, WS1.3b, WS1.3c, WS1.3d, WS1.3e, WS1.3f, WS1.3g, WS2a, WS2b, WS2c, WS2d | Investigations of enzyme activity, including numerical analysis of data and graphical representation of results. (PAG B3) | |
B1.2d explain the mechanism of enzyme action | the role of enzymes in metabolism, the role of the active site, enzyme specificity (lock and key hypothesis) and factors affecting the rate of enzyme controlled reactions (pH, temperature, substrate and enzyme concentration) | M1a, M1c, M3d, M4b | WS2a, WS2b, WS2c, WS2d | Demonstration of the effect of amylase on a baby rice paste. (PAG B3) Investigation of enzyme controlled reactions. (PAG B3) |