Biology (Combined Science) · GCSE · OCR · OCR GCSE Combined Science A (Gateway Science) — Biology — Higher (J250) · Specification point · B5.1 · Genes, inheritance and selection
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B5.1 Inheritance
Summary Inheritance relies on the genetic information contained in the genome being passed from one generation to the next, whether sexually or asexually. The characteristics of a living organism are influenced by the genome and its interaction with the environment. Underlying knowledge and understanding Learners should be familiar with the idea of heredity as the process by which genetic information is passed from one generation to the next. They should have a simple model of chromosomes, genes and DNA. Common misconceptions Learners commonly struggle to appreciate the physical relationships between the nucleus, genetic material, the genome, chromosomes and genes. Accurate definitions of these terms will help learners’ explanations in this topic. Learners
often have well-developed (although not necessarily scientifically accurate) explanations for inheritance before undertaking GCSE study. Some examples include that intra-specific variation is as a result of defects in development or that acquired characteristics can be inherited. Care must also be taken with the concept of dominant and recessive alleles. Whether an allele is dominant or recessive does not affect the mechanism of inheritance of the allele, but is an observed pattern in the phenotype of organisms. Many learners assume that the dominant allele ‘dominates’ the recessive allele preventing its expression (which is not the case) or that the recessive allele is actually just an absence of the dominant allele (also not generally the case).
| Reference | Mathematical learning outcomes | Maths skills |
|---|---|---|
BM5.1i | understand and use direct proportions and simple ratios in genetic crosses |
M1c |
BM5.1ii | understand and use the concept of probability in predicting the outcome of genetic crosses | M2e |
BM5.1iii | extract and interpret information from charts, graphs and tables | M2c and M4a |
| Learning outcomes | To include | Maths | Working scientifically | Practical suggestions |
|---|---|---|---|---|
B5.1a explain the following terms: gamete, chromosome, gene, allele/variant, dominant, recessive, homozygous, heterozygous, genotype and phenotype | Use of alleles to work out the phenotype of progeny. | |||
B5.1b describe the genome as the entire genetic material of an organism | ||||
B5.1c describe that the genome, and its interaction with the environment, influence the development of the phenotype of an organism | use of examples of discontinuous (e.g. eye colour) and continuous variation (e.g. weight and height) | |||
B5.1d recall that all variants arise from mutations, and that most have no effect on the phenotype, some influence phenotype and a very few determine phenotype | ||||
B5.1e explain the terms haploid and diploid | ||||
B5.1f explain the role of meiotic cell division in halving the chromosome number to form gametes | that this maintains diploid cells when gametes combine and is a source of genetic variation | |||
B5.1g explain single gene inheritance | in the context of homozygous and heterozygous crosses involving dominant and recessive genes | M2c, M4a | Prediction of the probability of phenotype for genetic crosses. Investigation into probability by suitable example (e.g. coin toss or die roll). | |
B5.1h predict the results of single gene crosses | the use of Punnett squares | M1c, M2c, M2e,M4a | ||
B5.1i describe sex determination in humans using a genetic cross | the use of Punnett squares | M1c, M2c, M2e, M4a | ||
B5.1j recall that most phenotypic features are the result of multiple genes rather than single gene inheritance |