Monohybrid crosses using genetic diagrams

A monohybrid cross predicts the inheritance of one characteristic. It shows which allele each parent can pass on, then combines the parental alleles to find the possible offspring genotypes.

An allele is a version of a gene. An individual has two alleles for the gene, but each gamete carries only one. The combination of alleles is the genotype; the observable form of the characteristic is the phenotype.

For the crosses below, suppose flower colour is controlled by a dominant allele $$P$$ for purple and a recessive allele $$p$$ for white. A plant with $$PP$$ or $$Pp$$ has purple flowers because one dominant allele is enough to produce the purple phenotype. A plant must have $$pp$$ to have white flowers.

A genotype with two identical alleles, such as $$PP$$ or $$pp$$, is homozygous. A genotype with two different alleles, such as $$Pp$$, is heterozygous.

Punnett square: two heterozygous parents

In a Punnett square, the possible gamete alleles from one parent go across the top and those from the other parent go down the side. Each cell combines one allele from each parent to show a possible offspring genotype.

For a cross between two heterozygous parents, $$Pp \times Pp$$, each parent can pass on either $$P$$ or $$p$$:

The four cells give a predicted genotype ratio of 1 $$PP$$ : 2 $$Pp$$ : 1 $$pp$$. Three cells have at least one dominant allele and therefore predict purple flowers; one has two recessive alleles and predicts white flowers. The predicted phenotypic ratio is 3 purple : 1 white, or 3 dominant : 1 recessive.

Punnett square: heterozygous and homozygous recessive parents

For a cross between a heterozygous parent and a homozygous recessive parent, $$Pp \times pp$$, the first parent can pass on $$P$$ or $$p$$. The recessive parent can pass on only $$p$$.

Two cells show $$Pp$$ and two show $$pp$$. The predicted phenotypic ratio is therefore 1 purple : 1 white, or 1 dominant : 1 recessive.

These ratios are predictions of the relative likelihood of each phenotype. The actual numbers in a particular group of offspring may not match the predicted ratio exactly.